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- etymologie
Wat (wie) is PDE5 inhibitor - definitie
PDE5 inhibitor
![Chemical structure of [[sildenafil]] (Viagra), the prototypical PDE5 inhibitor](https://commons.wikimedia.org/wiki/Special:FilePath/Sildenafil.svg?width=200 "Chemical structure of [[sildenafil]] (Viagra), the prototypical PDE5 inhibitor")
DRUG USED TO BLOCK THE DEGRADATIVE ACTION OF CGMP-SPECIFIC PHOSPHODIESTERASE TYPE 5 ON CYCLIC GMP IN THE SMOOTH MUSCLE CELLS LINING THE BLOOD VESSELS SUPPLYING VARIOUS TISSUES
PDE5 inhibitors; Phosphodiesterase V inhibitors; Pde5 inhibitor
A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues. These drugs dilate the corpora cavernosa of the penis, facilitating erection with sexual stimulation, and are used in the treatment of erectile dysfunction (ED).
Polymerisation inhibitor
CHEMICAL ADDITIVE THAT SUPPRESSES POLYMERIZATION
Polymerization inhibitor
Polymerisation inhibitors (US: polymerization inhibitors) are chemical compounds added to monomers to prevent their auto-polymerisation. Unsaturated monomers such as acrylates, vinyl chloride, butadiene and styrene require inhibitors for both processing and safe transport and storage.
CDK inhibitor
DRUG CLASS; AN EC 2.7.11.* (PROTEIN-SERINE/THREONINE KINASE) INHIBITOR THAT INTERFERES WITH THE ACTION OF CYCLIN-DEPENDENT KINASE (EC 2.7.11.22).
Purvalanol A; CDK4/6 inhibitor
A CDK (cyclin-dependent kinase) inhibitor is any chemical that inhibits the function of CDKs. They are used to treat cancers by preventing overproliferation of cancer cells.
